The BBC Antiques Roadshow presenter, who was previously a director of Roseberys in London, returned to the UK with her husband Marc Allum in 2012 after eight years in France and launched her online business Hand of Glory Antiques.
Following the opportunity of a vacant shop near their home in Chippenham, Lloyd has taken on the lease at 34 Market Place in the town.
She said: “I have been storing my stock in a coach house near my home and clients have wanted to come and see what I have, after finding me online.
“Having a shop will give me the opportunity to present all my stock including my larger items. There will be space to create room sets here.”
Having traded online for eight years, Lloyd added: “Selling online is great and when buyers know what they want it works really well, but many people like to browse and have the hands-on experience. So trading from the shop and my website will work really well.”
Lloyd has hired a shop assistant who worked at the former location when it traded as a vintage store.
The shop, which will be stocked with a mix of antiques and modern design, will open on Saturday, November 9, and trade four days a week, Wednesday-Saturday, and by appointment at other times.