Five of the pieces are by Thomas Chippendale and with the current auction high of £1.6m set back in 1993 in the same rooms for the Anglesey desk, there is the possibility that figure could be bettered several times over.
Topping the bill with a guideline of £2.5m-4m is the so-called Kenure Cabinet, a Chinoiserie fantasy created during the late 1750s and designed as a display vehicle for the costly and fashionable oriental porcelains imported from the Far East.
The cabinet is thought to have been made for Sir Roger Palmer, who inherited Kenure Park County Dublin in 1811 where the piece remained until 1964 when his descendants sold it at auction to the family who have owned it since.
The cabinet is very similar to an example in Dumfries House, Ayrshire, whose exceptional Chippendale collection would have certainly broken auction records had it gone under the hammer at Christie's last summer as originally planned. In the event the house and contents were saved for the nation in a private treaty sale masterminded by the Prince of Wales.
The 12-lot sale will be an evening event held immediately after Christie's daytime sale of works of art.