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It was written in reply to a young Chester architect who had emigrated to the Pittsburgh in 1930 and, finding work hard to get, had written to Miss Harlow who was staying at the city’s William Penn Hotel, asking about the possibility of working as a set designer in Hollywood.

In her full reply Miss Harlow says the movie world is in a “deplorable condition” adding: “At this time I would advise no-one to go to Hollywood... Actors and actresses with names that mean box office attraction are now having a struggle to live.”

She signs the bad news: “Most cordially yours, Jean Harlow.”

Two years later, the architect returned to Chester and employment with the County Council but he always kept the kindly letter and now his niece is putting it into Byrne’s sale where it is estimated at up to £500.